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1.
Famous quote from 80's tv sitcom "Different Strokes"

Used in normal conversation when speak doesn't understand.
"what you talkin bout willis?" -- translates to: "I did not understand"
av Butifuco 17. november 2003
 
2.
Implying that someone else is crazy when they're merely pointing out your foolishness.
Willis: Don't you think you'd better put the lid on that blender full of gunk before you plug it in?

Lil' Fool: What you talkin bout willis? (as he plugs in the blender)
av Liv Pooleside 28. januar 2006